GI Maps Stool Test: What Your GI Doctor May Be Missing

Do you have constant gastrointestinal problems?

Have you been to GI doctors, who can never find anything wrong with you despite how bad you feel?

Have you had stool tests done by GI “specialists” but nothing ever comes up to explain the way you feel?

Do you have acne on different parts of your body that just won’t go away?

Do you have anxiety that won’t go away even if you’ve tried everything to get rid of it? Are you always constipated or having diarrhea?

Dysbiosis is not a classic infection

If this sounds like you, there’s a strong possibility that your microbiome is not balance. You likely have a larger proportion of bad bacteria, parasites, and candida to the amount of good probiotic bacteria in your gut. This is called Dysbiosis. This disruption in your gut microbiome can affect your neurotransmitters in your brain leading to depression, anxiety and impaired cognitive function. It can also lead to acne, eczema, rosacea, psoriasis and breakouts on you bum, arms and other places.

WHAT IS THE GUT MICROBIOME?

The microbiome is the microbes on the outside as well as the inside of your body. They colonize your skin, mucosal membranes, intestines, mouth, nose, throat. These microbes influence your brain function, diabetes, immune system function, hormones, weight loss, psychiatric health and more.

The GI Maps Stool test is a SPECIALTY stool test that tests WAY more than you will ever get at a GI specialist. This stool test checks for the following:

PATHOGENS: The classic bacteria that cause acute symptoms in the GI tract and bowel changes.

bacterial pathogens

The GI-MAP includes pathogens (bacterial, parasitic, and viral) commonly known to cause intestinal gastro inflammation. It’s important to note that not all individuals with positive findings for pathogens will present with symptoms. Many factors, including the health of the individual, the transient nature of some pathogens, and the presence and expression of virulence factors all contribute to an individual’s symptoms.

H. PYLORI: Can cause ulcers, reflux, gastritis and stomach cancer

h pylori

Recent studies have shown that nearly 50% of the world’s population may harbor H. pylori. Many carriers are asymptomatic. Additionally, in early phases of colonization, people may experience low stomach acid followed by a change to high acid. Over time, additional H. pylori strains may colonize, including those with Virulence Factors and increased disease potential.

ANTIBIOTIC RESISTANT GENES: Tests for antibiotic resistance to the most commonly used antibiotics to treat h, pylori.antibiotic resistant genes

NORMAL/COMENSAL BACTERIA: beneficial bacteria that when too low or too high can indicate imbalance in the gut microbiome.

low good bacterial
This person happened to be on a ketogenic diet, which greatly lowers the amount of normal bacteria flora in the gut. The two major species bifidobacterium and lactobacillus have major roles in protecting against many diseases.

Trillions of microorganisms inhabit the human intestine to make up a complex ecosystem that plays an important role in human health. Good bacteria extract nutrients from our diets, maintain gut barrier function (protect against leaky gut), produce vitamins (biotin and vitamin K), and protect against colonization by potential pathogens (act as security guards in the stomach).

OPPORTUNISTIC BACTERIA: These are not tested routinely. These are bacteria that when they become too high, they can become pathogenic and cause problems

opportunistic bacteria

Many bacteria measured on the GI-MAP are considered opportunistic pathogens, as they only cause disease and illness in some individuals, particularly the immune-compromised. How do you know if your intestinal immune system is compromised? This stool test checks for that too!

Many individuals come into contact with opportunistic bacteria and experience no symptoms. Most sources consider these microbes to be normal in the stool. However, they can cause gastroenteritis and inflammation at high levels in vulnerable patients (someone with a low Secretory IgA).

Symptoms may include diarrhea, loose stools, abdominal pain, or even constipation. Overgrowth and excessive colonization by opportunistic bacteria may occur when the commensal bacteria are impaired by poor diet, antibiotic use, parasitic infection, or a weakened immune system. When Leaky Gut is present, these microbes could escape the lumen of the gut and infect extra-intestinal sites.

AUTOIMMUNE TRIGGERING BACTERIA: Bacteria that is associated with influencing the immune system to develop autoimmunity. For example: Rheumatoid Arthritis & Ankylosing Spondylitis can be caused by Klebsiella.

Klebsiella

FUNGI/YEAST/CANDIDA:

candida and yeast

Fungal organisms are commonly found in the human digestive tract, but fungal overgrowth can cause illness in susceptible individuals. Fungal growth may be localized in the body. For instance, Candida spp. may be high in the large intestine but normal in the small intestine, and vice versa. You may have candida overgrowth if you have a white tongue, constant yeast infections, brain fog, nail/fungal infections, joint pain.

What are common causes of yeast overgrowth?

  1. Antibiotic use
  2. High intake of sugar, starches, beer, bread, nuts, corn, cheese
  3. Low stomach acid
  4. Impaired immune function
  5. Dysbiosis (increased number of bad bacteria to good bacteria)

 

VIRUSES: Viral DNA can be found in the stool in an active disease state. Viruses also influence the immune system to switch on an autoimmune disease.

virus
the EBV should be <dl (below detectable limits). Even values that are present but not greater than lab range may still cause symptoms.

Viruses are common triggers of fatigue, autoimmune diseases like Hashimoto’s Thyroiditis, Sjogrens Syndrome, Multiple Sclerosis, Gastric Cancer and Irritable Bowel Disease.

PROTOZOAN PARASITES: Other parasites that are not routinely tested for.

parasite

A parasite is an organism that lives and feeds on a host organism at the expense of the host. The GI-MAP tests for pathogenic parasites and protozoa (some of which are non-pathogenic) most commonly occurring in the GI tract

These protozoan parasites are NOT commonly tested for at your regular GI doc’s office. Some people may not express symptoms in the gut, but instead they may experience seizures, acne, eczema or an inability to absorb iron.

WORMS:

This is usually an uncommon finding in my patients, but for those who travel outside of their usual country it’s very important to check for worms. Most of the time you would see them in your stool or experience an itchy anus.

  1. Hookworm
  2. Roundworm
  3. Whipworm
  4. Tapeworm

Now we are at my favorite part of the GI Maps test – Intestinal Health Markers:

DIGESTION:

Digestion

Steatocrit: Fat malabsorption in the stool, signaling poor gallbladder function.

Pancreatic Elastase-1: This measures the amount of enzymes your pancreas is putting out. This is one of the reasons why people bloat after they eat, they don’t have enough enzymes being secreted to break down the foods well.

 

ESTROGEN ELIMINATION:

estrogen

Beta-Glucoronidase: measures if you are eliminating old estrogen efficiently. If there is a degree of gut dysbiosis and liver congestion your old estrogen will not be eliminated properly. It will be recycled back into the body. This impacts both men and women.

OCCULT BLOOD:

Fecal Immunochemical Testing (FIT): Screen for colon cancer

INTESTINAL IMMUNE SYSTEM:

LOW SIG A

HIGH SIGA

Secretory IgG (SIgA): the intestinal immune system….the security guards of the gut. This is your first line of defense against pathogens, parasites, candida, food antigens. If there is a low SIgA that means your security guards not doing their job and things are getting through that should not be there. The immune system is being suppressed by too many things bombarding it. Chronic stress and pain, eating foods like wheat and dairy, corn, antibiotics, pesticides, grains usually suppress the immune system response.

When there is a high SIgA, that is your immune system rising to the occasion of battling something. It’s trying to do it’s job. It’s a signal that there’s a war going on in there.

When you have a low SIgA that makes you more vulnerable to getting sick with slower recovery. It means you’re more likely to feel symptoms from opportunistic bacteria than someone who has a robust immune response.

WHEAT ANTIBODIES:

Gliadin Antibodies: Antibodies to wheat will first appear in the gut before they ever appear on a blood test. They are contained within the gut until they can no longer be contained anymore. This means your immune system is creating antibodies everytime you eat wheat, and you DON’T need to have Celiac Disease to have a problem with wheat!

INFLAMMATION:

CALPROTECTIN

Calprotectin: One of the most studied markers of intestinal inflammation. It points out that the intestines are inflamed from either infections, medications or something in the diet.

 

Please Note:

If you’d like to do this test, please email me or call our office: 954-630-1616. Diagnostic Solutions Labs uses insurances that have out of network benefits for $179. If you do not have insurance, the out of pocket cost is $359 through my office. Consultations to go over results & recommendations of how to fix the observed imbalances have a $125 consult fee.

Author: Melissa Mullin

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